As for the Reds, they had their Boxing Day match against Leeds called off, with several first-team players recovering from positive Covid tests between that Anfield penalty shoot-out victory over the Foxes and this encounter on the road.
Victory for Jurgen Klopp’s side will leave them three points off Man City, who play one day later.
Here’s all you need to know ahead of the game.
When is the match?
The game kicks off at 8pm GMT on Tuesday 28 December at the King Power Stadium.
Where can I watch it?
Like all the midweek games in this round of fixtures, the match will be shown live on Amazon Prime Video across all mobile devices with the Prime Video app and the desktop website. It is not scheduled for broadcast on any terrestrial or satellite TV channel, but can be watched on TVs compatible with the Prime Video app or through Apple TV, Chromecast and other plug-ins.
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What is the team news?
The Foxes still have a big injury list to contend with, including James Justin, Wes Fofana, Patson Daka, Jonny Evans and now Ricardo Pereira, who was injured in the League Cup loss against the Reds. Ryan Bertrand also pulled up in the warm-up at the weekend so must be considered a doubt, as is Caglar Soyuncu. Jamie Vardy and Wilfred Ndidi should play after being unused subs against Man City.
Liverpool’s Boxing Day match against Leeds was called off so they have no new injury worries. Nat Phillips, Adrian and Harvey Elliott are their long-term absences, while Divock Origi still appears to be sidelined. Thiago has only just returned to training after Covid and might still miss out here, but Fabinho, Virgil van Dijk and Curtis Jones are all available after earlier negative tests and subsequent returns. Andrew Robertson is suspended so Kostas Tsimikas will play left-back.
LEI – Schmeichel; Castagne, Amartey, Vestergaard, Thomas; Ndidi, Tielemans, Soumare, Maddison; Iheanacho, Vardy
LIV – Alisson; Alexander-Arnold, Matip, Van Dijk, Tsimikas; Fabinho, Henderson, Oxlade-Chamberlain; Salah, Jota, Mane
Nowhere near as close an encounter as the recent League Cup meeting between the two; the gulf was evident as soon as the Reds made subs to bring senior players on last week and with a full-strength team in place, Klopp’s side should brush past a Foxes defence lacking organisation and an ability to withstand set pieces. Leicester 1-4 Liverpool.